ExoGAG Cerebro Spinal Fluid

ExoGAG Cerebro Spinal Fluid

The ExoGAG Cerebro Spinal Fluid precipitation reaction is based on the interaction between the precipitation solution and glycosaminoglycans located on the exosome surface. After a simple incubation, the exosomes can be isolated by a short centrifugation. This patented system allows the isolation of exosomes from a cerebro spinal fluid sample with a minimal amount of co-precipitated material, such as protein or genetic material (DNA, RNA, or microRNA).

Cerebrospinal fluid is body fluid flows in and around the hollow spaces of the brain and spinal cord, and between two of the meninges. It is made by tissue called the choroid plexus in the ventricles (hollow spaces) in the brain. Although, cerebrospinal fluid derives from blood plasma, it does not contain erythrocytes and is nearly protein-free, but it presents extracellular vesicles (among them exosomes).
Given its contact with the brain and the spinal cord, it is the most informative biofluid for studies of the central nervous system in both physiological and pathological conditions. However, in contrast with others biofluids, its collection is through an invasive method (lumbar punction).
Exosomes isolated from cerebrospinal fluid represent a good potential alternative to tissue biopsy.

This ExoGAG Cerebro Spinal Fluid is manufactured in Spain by Nexotech.