ExoGAG Saliva

ExoGAG Saliva

The ExoGAG Saliva precipitation reaction is based on the interaction between the precipitation solution and glycosaminoglycans located on the exosome surface. After a simple incubation, the exosomes can be isolated by a short centrifugation. This patented system allows the isolation of exosomes from a saliva sample with a minimal amount of co-precipitated material, such as protein or genetic material (DNA, RNA, or microRNA).

Saliva is a complex biofluid produced and secreted by salivary glands in the mouth, but also by the oral microbiome and the epithelial oral cells. It is about 99% water and contains electrolytes, proteins, lipids, metabolites, cell-free nucleic acids, microbial agents and extracellular vesicles (among them exosomes).
Exosomes isolated from saliva are an attractive source of biomarkers due to this biofluid characteristics: easy accessibility, non-invasive methods of collection, and fewer compliance problems.
Moreover, the analysis of exosomes in saliva represents a potentially cost-effective approach for the screening of large populations and performing follow-up studies

This ExoGAG Saliva is manufactured in Spain by Nexotech.