Recombinant SARS-CoV-2 Nucleoprotein (HEK)
The Recombinant SARS-CoV-2 Nucleoprotein (HEK) is For Research Use Only
Description: Recombinant Human Coronavirus SARS-CoV-2 Nucleoprotein
NCBI Accession Number: MN908947
Sequence: Met1-Ala419
Expression System: HEK293 cells
Tag: HIS Tag C-Terminus
Purification: Affinity chromatography
Extinction Coefficient: 43890 M-1.cm-1 Abs 0.1% (=1 g/l) 0.943 assuming all pairs of Cys residues form cystine
Predicted Molecular Weight: 46.5 kDa
SDS Page: Approx. 50 kDa
Concentration: 1 mg/ml
Size: 100µg
Purity: >95% by SDS PAGE
Formulation: PBS
Endotoxins: Negative on cell-based assay
Activity: Recognized by Covid-19 positive patients serum samples.
Stability and Storage: Store at -20°C. Avoid repeated freeze-thaw cycles. Stable one week at 2 to 8°C after reconstitution under sterile conditions. Stable 12 months -20°C to -80°C after reconstitution under sterile condition.
Alternative Names: SARS-CoV nucleoprotein, Nucleocapsid protein, N protein
Product Background
Nucleoprotein (N protein/ Nucleocapsid protein) is one of four structural proteins of Coronavirus (SARS-Cov, SARS-Cov-2, MERS amongst other). The N protein primary function is to package the viral SARS-Cov-2 RNA genome within the viral envelope to form the helical nucleocapsid. N protein is a major immunogen and is highly expressed in infected cells at the early stage of infection.
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