ILite® Anti-CD20 ADCC Activity Set is for Research Use Only in the US.  Not to be used for Diagnostic Procedures.

Eagle Biosciences is proud to announce the launch of the iLite ADCC Activity Assay product line and the iLite anti-CD20 ADCC Activity Set.

Rituximab, a chimeric monoclonal antibody against CD20, was one of the first therapeutic antibodies within the oncology field to receive approval by the FDA in 1997. Ever since biosimilar and innovative biologicals with similar mechanism of action have been developed and marketed.

Antibody-dependent cell-medicated cytotoxicity (ADCC) can now, using our new iLite®ADCC Activity Assays, be measured in a straight forward, sensitive and reproducible manner.

ILite® Anti-CD20 ADCC Activity Set is a great addition to EagleBio’s Drug Monitoring kit Line which offers a unique grouping of products that provide incredible value to pre-clinical and clinical pharmacology studies, cancer research, and more specifically anti-tumor therapeutic investigation and more.

Key Advantages

The iLite® anti-CD20 ADCC Activity Set

  • Comprehensive kit– Contains 3 different genetically modified cell lines (components also available separately):
    1. Reporter Effector cell,
    2. Positive Target cell
    3. Negative Target cell
  • Fast- results in 5 hours- this set of cells enables measurements of an anti-CD20 drug’s ability to induce ADCC,
  • Easy- NO Cell culturing isrequired
  • Flexible– Effector cells, which can be used with any Target cell, include a normalization readout which can adjust for differences in cell counts.

 Assays below are For Research Use Only.

EagleBio’s New Drug Monitoring Assays:

Eagle Biosciences is pleased to offer 3 new assays to the Drug Monitoring Assay Kit line which offers a unique grouping of products that provide incredible value to pre-clinical and clinical pharmacology studies, cancer research, and more specifically antitumor therapeutic investigation and more.

      • NF alpha Neutralization Rate/Adalimumab ELISA Assay Kit
        • Simultaneously determination:

          • Free TNFα target antigen
          • Available therapeutic antibody Adalimumab
          • Adalimumab’s ability to neutralize TNFα
      • TNF alpha Neutralization Rate/Infliximab ELISA Assay Kit:
        •  Simultaneously determination:
          • Free TNFα target antigen
          • Available therapeutic antibody Infliximab
          • Infliximab’s ability to neutralise TNFα
      • Deoxynivalenol ELISA Assay Kit
        • Unique Assay for Determination:
          • Deoxynivalenol in food and feed crops

 

 

EagleBio’s DM1 Antibody Drug Conjugate (ADC) ELISA ASSAY Kit was recently used in a Texas Tech University Health Sciences Center study.  This assay is part of our Drug Monitoring Assay Kit line which offers a unique grouping of assays that provide incredible value to pre-clinical and clinical pharmacology studies, cancer research, and more specifically antitumor therapeutic investigation and more.

Yao H-P, Feng L, Zhou J-W, Zhang R-W, Wang M-H. Therapeutic evaluation of monoclonal antibody-maytansinoid conjugate as a model of RON-targeted drug delivery for pancreatic cancer treatment. American Journal of Cancer Research. 2016;6(5):937-956. PMID:27293990

“Blood samples were collected at different time intervals. DM1-coupled Zt/g4 was measured using a DM1 antibody ELISA kit (EagleBiosciences, Inc., Nashua, NH).”

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