HLA-A*02:01 (YLLEMLWRL) Class I Peptide-MHC
What are MHC molecules? Major histocompatibility complex (MHC) molecules play an important role in the acquired immune system of vertebrates. MHC molecules present peptides derived from pathogens on the cell surface so that T-cells can determine the appropriate immune response. The MHC also plays a role in mediating leukocyte interactions, determining compatibility for organ transplants,…
Immune Monitoring COVID-19 Cells infected with SARS-CoV-2 are only visible to CD8+ T cell after virus proteins have been processed and presented by MHC class I molecules – and only then are the CD8+ T cell able to eradicate the infection. While antibodies against the COVID-19 virus are important to prevent or minimize infection, CD8+…
Through our collaboration with ImmunAware, we are excited to offer a new range of products: easYmer MHC Tetramers. This product allows laboratories to easily generate monomers using their choice of peptide. The resulting monomers can also be easily tetramerized using fluorophore conjugated streptavidin. These tetramers can then be used to stain cognate T cells for…