Mouse Anti-Rat Parvalbumin Monoclonal IgG2a Antibody
Parvalbumin is a calcium-binding protein predominantly expressed in fast-spiking GABAergic interneurons. It plays a crucial role in buffering intracellular calcium and regulating neuronal excitability and synaptic timing.
Alterations in parvalbumin-expressing interneurons have been implicated in a range of neurological and psychiatric disorders, including Alzheimer’s disease, schizophrenia, autism spectrum disorders, and age-related cognitive decline. Loss of parvalbumin function disrupts inhibitory signaling, leading to network hyperexcitability and impaired cognitive processing.
As a marker of interneuron health and circuit integrity, parvalbumin is a valuable target for studying neural dysfunction and developing interventions aimed at restoring excitatory-inhibitory balance in the brain.
This Mouse Anti-Rat Parvalbumin Monoclonal IgG2a Antibody is manufactured in Canada by StressMarq.
| Size | 100 µg |
| Group | |
| Alpha Chain | |
| Beta Chain | |
| Peptide | |
| Peptide Source | |
| Format | |
| Buffer | |
| Concentration | 1mg/mL |
| Storage | -20°C |
| Alternative Names | Parvalbumin alpha, PRVA_HUMAN, PVALB |
