Mouse Anti-Nitrotyrosine Monoclonal IgG2a Antibody
Nitrotyrosine is a post-translational modification formed by the nitration of tyrosine residues, often mediated by reactive nitrogen species such as peroxynitrite. It serves as a biomarker of nitrosative stress and is increasingly recognized for its role in neurodegenerative disease pathology. Nitrotyrosine-modified proteins are frequently detected in Alzheimer’s disease, Parkinson’s disease, and ALS, where they correlate with inflammation-induced tissue injury. Enzymes such as myeloperoxidase, cytochrome P450s, and superoxide dismutase catalyze tyrosine nitration, disrupting protein function and contributing to neuronal damage. As a marker of oxidative and nitrosative stress, nitrotyrosine provides mechanistic insight into redox imbalance and may serve as a diagnostic and therapeutic target in neurodegeneration.
This Mouse Anti-Nitrotyrosine Monoclonal IgG2a Antibody is manufactured in Canada by StressMarq.
| Size | 100 µg |
| Group | |
| Alpha Chain | |
| Beta Chain | |
| Peptide | |
| Peptide Source | |
| Format | |
| Buffer | |
| Concentration | 1 mg/mL |
| Storage | -20°C |
| Alternative Names | Nitrotyrosine, Nitro tyrosine, 3-Nitrotyrosine |
