The **Hamster (CHO) Legumain ELISA Kit** is designed to quantify legumain, an asparaginyl endopeptidase primarily localized in the lysosomes of many cell types, including Chinese Hamster Ovary (CHO) cells. Legumain plays a key role in protein processing, antigen presentation, and extracellular matrix (ECM) remodeling. It is also implicated in pathological processes such as tumor progression, fibrosis, and inflammatory responses. Because legumain expression is closely tied to cellular stress, lysosomal function, and tissue remodeling, it serves as an informative biomarker for studying both normal physiological and disease-related cellular pathways.
In **research settings**, this ELISA kit is frequently used to monitor legumain expression in CHO cell lines—an important system for biologics manufacturing—as an indicator of cell health, stress, and productivity. Researchers also employ it in studies of cancer biology, immune regulation, and metabolic disorders, where altered legumain activity can reflect changes in tumor invasiveness, immune cell activation, or tissue degradation. Its quantitative sensitivity makes it suitable for tracking treatment effects, evaluating genetic modifications, and modeling disease mechanisms in vitro or in animal studies involving hamster-derived cells.
In **preclinical and translational contexts**, legumain measurements can support the development and quality control of therapeutic proteins produced in CHO cells by identifying stress-related shifts that may affect yield or product quality. Although not used directly in human clinical diagnosis, data from hamster legumain assays can help predict how cellular stress pathways might impact therapeutic production or toxicity. In comparative pathology and drug development, legumain quantification also aids in assessing biological responses relevant to human diseases, particularly in oncology and fibrosis research.
This product is manufactured in USA by Eagle Biosciences.
| Size | 1 x 96 Well |
| Sensitivity | 0.131 ng/mL |
| Dynamic Range | 0.3125 ng/mL – 20 ng/mL |
| Incubation Time | 2 hours 50 minutes |
| Sample Type | Tissue Culture Fluids |
| Storage | 2-8°C |
| Alternative Names | 1. This assay is also known as a **Hamster (CHO) Legumain Detection ELISA Kit**. 2. Many researchers refer to it as a **CHO Cell Legumain Quantification Kit**. 3. It may also be called a **Hamster Legumain Immunoassay Kit**. 4. Some protocols describe it as a **CHO-Derived Legumain Measurement ELISA Kit**. 5. It is sometimes listed as a **Hamster (CHO) Legumain Analysis Kit**. 6. Another common name is a **CHO Cell Legumain Quantitative ELISA Kit**. 7. It can also be described as a **Hamster Legumain Detection Assay Kit**. 8. In some catalogs, it is labeled as a **CHO Line Legumain Enzyme Immunoassay Kit**. |