The C1s/C1-INH complex actively controls the complement system’s classical pathway, crucial for the body’s innate immune defense against infections. This complex forms when C1 inhibitor (C1-INH) binds with C1r and C1s, effectively regulating the proteolysis-based activation cascade and preventing overreaction of the immune system. In diseases like Hereditary Angioedema (HAE) and Systemic Lupus Erythematosus (SLE), the altered levels of the C1s/C1-INH complex provide key insights into immune activity, establishing its importance as a biomarker for monitoring immune responses.
This product is manufactured in Netherlands by Hycult Biotech.
| Size | 1 x 96 Well |
| Sensitivity | 1.56 ng/mL |
| Dynamic Range | 1.56 – 100 ng/mL |
| Incubation Time | 1 hour 45 minutes |
| Sample Type | Serum, Plasma |
| Immunogen | |
| Source Species | |
| Specificity | |
| Expression System | |
| Clone | |
| Group | |
| Alpha Chain | |
| Beta Chain | |
| Peptide | |
| Peptide Source | |
| Format | |
| Buffer | |
| Concentration | |
| Storage | 2-8°C |
| Alternative Names | Classical Pathway Inhibition Complex |
| Instructions For Use | https://eaglebio.com/wp-content/uploads/2025/03/HK399_C1s-C1-INH_Complex_ELISA_Kit_Package_Insert.pdf |
| MSDS | https://eaglebio.com/wp-content/uploads/2025/03/HK399_C1s-C1-INH_Complex_ELISA_Kit_SDS.pdf |