Anti-Deamidated Gliadin Peptides (DGP) IgG ELISA Kit

$515.00

The Anti-Deamidated Gliadin Peptide (DGP) IgG ELISA Kit is for the quantitative measurement of IgG class antibodies directed against Deamidated Gliadin Peptides (DGP) in human serum or plasma. The Anti-Deamidated Gliadin Peptide (DGP) IgG ELISA Kit is for research use only and not intended for diagnostic procedures.

SKU: DKO106 Category: Tags: , ,

Anti-deamidated gliadin peptides (anti-DGP) IgG antibodies are autoantibodies directed against gliadin peptides that have undergone deamidation, a process catalyzed by tissue transglutaminase. Deamidation enhances the immunogenicity of gliadin, a component of gluten, triggering a stronger immune response in individuals with celiac disease. Anti-DGP IgG has emerged as a valuable serologic marker, particularly in cases where traditional markers like anti-tTG IgA may be inconclusive.
In clinical settings, anti-DGP IgG is especially useful for diagnosing celiac disease in patients with selective IgA deficiency or in young children, where IgA responses may be underdeveloped. It can serve as an alternative or complementary marker when anti-tTG IgA is negative but suspicion of celiac disease remains high. When combined with other serologic tests, it enhances diagnostic accuracy and may reduce the need for intestinal biopsy in certain cases. In research, anti-DGP IgG helps to further understand gluten-related immune responses, monitor dietary adherence, and explore non-classical or extra-intestinal manifestations of gluten sensitivity. It also plays a role in developing and validating novel diagnostic strategies for celiac disease and related gluten-mediated disorders.

This product is manufactured in Italy by Diametra.

Size 1 x 96 Well
Sensitivity 0.13 AU/mL
Dynamic Range 15 – 240 AU/mL
Incubation Time 1 hour 15 minutes
Sample Type Serum, Plasma
Immunogen
Source Species
Specificity
Expression System
Clone
Group
Alpha Chain
Beta Chain
Peptide
Peptide Source
Format
Buffer
Concentration
Storage 2-8°C
Alternative Names DGP, Modified gliadin peptides, immunogenic gliadin peptides
Instructions For Use https://eaglebio.com/wp-content/uploads/2014/06/DCM106_Anti-DGP_IgG_ELISA_Kit_Package_Insert.pdf
MSDS https://eaglebio.com/wp-content/uploads/2025/03/DCM106_Anti-DGP_IgG_ELISA_Kit_SDS.pdf

Product Citations