The Anti-Aprotinin Antibodies (IgG) ELISA Kit is designed to detect and quantify IgG-class antibodies against aprotinin, a small protease inhibitor commonly used in surgical and therapeutic applications to reduce bleeding. Aprotinin, derived from bovine lung tissue, can elicit an immune response in some individuals, leading to the production of anti-aprotinin antibodies. Monitoring these antibodies is important for assessing potential immune reactions, therapeutic efficacy, and safety in clinical or experimental settings.
In this ELISA format, microplate wells are coated with aprotinin to capture specific IgG antibodies from serum or plasma samples. Following antigen–antibody binding, an enzyme-conjugated secondary antibody produces a colorimetric signal proportional to the concentration of anti-aprotinin IgG. This method offers high sensitivity, specificity, and reproducibility for detecting antibodies that may impact therapeutic outcomes or provoke adverse immune responses.
Applications of the Anti-Aprotinin Antibodies (IgG) ELISA Kit include evaluating immune responses in patients receiving aprotinin therapy, screening for antibody-mediated adverse effects, and studying the immunogenicity of aprotinin-containing pharmaceuticals. By providing quantitative insights into anti-aprotinin IgG levels, the kit helps researchers and clinicians better understand antibody-mediated interactions that may influence efficacy, safety, and patient management.
This product is manufactured in Germany by CellTrend GmbH.
| Size | 1 x 96 Well |
| Sensitivity | 12.5 U/mL |
| Dynamic Range | 12.5 U/ml – 200 U/ml |
| Incubation Time | 2 hours |
| Sample Type | serum |
| Storage | 2-8°C |
| Alternative Names | aprotinin-specific IgG, aprotinin-targeting antibodies, anti-aprotinin IgG, aprotinin-reactive antibodies, or IgG antibodies against aprotinin |
