Human L-TGF-α (Media Grade)

$485.00

Human L-TGF-α is a cost-effective analogue of human transforming growth factor-α (TGF-α), engineered with a 14–amino acid N-terminal extension. Designed for mammalian cell culture, it supports cell survival and proliferation in serum-free or low-serum media and can substitute for native or recombinant TGF-α. L-TGF-α is effective in fibroblast, epithelial, and avian cell culture, with synergistic activity alongside L-EGF and LR3 IGF-I. This product is for research use only and not to be used in diagnostic procedures.

Human L-TGF-alpha is a low-cost analogue of human transforming growth factor-alpha (TGF-α) developed by GroPep® specifically for supplementation of mammalian cell culture to support the survival and proliferation of cells in serum-free or low serum culture. It can be used as a like-for-like replacement for native TGF-αor recombinant human TGF-α. It comprises the human TGF-αamino acid sequence plus a 14 amino acid N-terminal extension peptide.

L-TGF-α has applications in fibroblast and epithelial cell culture and has a higher affinity for avian Erb-1 receptors than native EGF, thus is a highly effective growth factor for vaccine production in avian cells. L-TGF-α has shown synergistic effects with L-EGF in keratinocyte growth and synergistic effects with LR3 IGF-I have been observed in various other cell lines.

This product is manufactured in Australia by GroPep Bioreagents.

Size 1 mg
Source Species Recombinant
Expression System Ecoli
Storage 2-8°C

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