The Eagle Biosciences Humanized Anti HER-2 ELISA Assay Kit detect levels of Trastuzumab (Herceptin) in human serum and plasma.

What is HER-2?

The Human Epidermal Growth Factor Receptor 2 gene (HER-2) can play a role in the development of breast cancer. This gene codes for a protein that are receptors on breast cells and helps the cell grow and divide normally. When regulation of the HER-2 gene gets disrupted or too many copies of the HER-2 gene are present in the cell, this can lead to an increased amount of the HER-2 protein on the cell surface. This causes the cell to start growing out of control and can develop into a tumor. Trastuzumab (Herceptin) is a drug that blocks the ability of the HER-2 protein on the surface of cells to receive chemical signals telling the cell to grow. This can slow or stop the growth of these breast cells and can also signal the immune system that these cells need to be destroyed. Measuring the levels of this drug in serum or plasma are important for evaluating the effectiveness of drug therapy.

Key Advantages of EagleBio’s Anti HER-2 ELISA

  • Excellent Specificity
  • High Sensitivity
  • Precise results under 2 hours

Eagle announces the introduction of an Intact MMAF ADC ELISA Assay Kit to its line of existing Antibody Drug Kits. This Intact MMAE Kit is the first of its kind, allowing for the measurement of conjugated antibody in a variety of sample types.

What is MMAF (Monomethyl auristatin F)?

MMAF is a new type of targeted therapy for cancer treatment. It is a synthetic antineoplastic agent that is a toxic compound; when linked to a monoclonal antibody (mAb) it gets directed to cancer cells. This drug treatment targets tumors and inhibits their growth by blocking the polymerization of tubulin in the cell. Measuring circulating specific ADC’s is importatnt for pre-clinical and clinical studies for the discovery of unique, targeted, safer, effective cancer treatments.

Key Advantages to Eagle Biosciences’s Antibody Drug Conjugates Assays:

  • Excellent Sensitity
  • Simple Procedure
  • Wide Dynamic Range
  • Quick Results: Under 3 hours
  • Versatile: multiple sample types and species

Related Kits:

MMAF Antibody Drug Conjugate (ADC) ELISA Assay Kit

MMAE Antibody Drug Conjugate (ADC) ELISA Assay Kit

Intact MMAE ADC ELISA Assay Kit

Eagle announces the introduction of an Intact MMAE ADC ELISA Assay Kit to its line of existing Antibody Drug Kits. This Intact MMAE Kit is the first of its kind, allowing for the measurement of conjugated antibody in a variety of sample types.

What is MMAE (Monomethyl auristatin E)?

MMAE is a new type of targeted therapy for cancer treatment. It is a synthetic antineoplastic agent that is a toxic compound; when linked to a monoclonal antibody (mAb) it gets directed to cancer cells. This drug treatment targets tumors and inhibits their growth by blocking the polymerization of tubulin in the cell. Measuring circulating specific ADC’s is importatnt for pre-clinical and clinical studies for the discovery of unique, targeted, safer, effective cancer treatments.

Key Advantages to Eagle Biosciences’s Antibody Drug Conjugates Assays:

  • Excellent Sensitity
  • Simple Procedure
  • Wide Dynamic Range
  • Quick Results: Under 3 hours
  • Versatile: multiple sample types and species

Related Kits:

MMAE Antibody Drug Conjugate (ADC) ELISA Assay Kit