CD59, an essential glycoprotein on cell surfaces, regulates complement-mediated lysis by inhibiting the membrane attack complex (MAC). As a guardian of cellular integrity, sCD59 prevents inflammation and thrombosis by blocking MAC formation. Its ubiquitous presence across mammalian cells underscores its role in immune regulation and T cell activation. CD59 gene mutations lead to deficiency, causing hemolytic anemia and cerebral infarction, highlighting its clinical importance. With levels ranging from 22 to 119 ng/ml in healthy plasma, sCD59 emerges as a crucial biomarker for immune health, offering therapeutic potential for complement-related disorders.
This product is manufactured in Netherlands by Hycult Biotech.
| Size | 1 x 96 Well |
| Sensitivity | 0.39 ng/mL |
| Dynamic Range | 0.39 – 25 ng/mL |
| Incubation Time | 3 hours 30 minutes |
| Sample Type | Plasma |
| Storage | 2-8°C |
| Alternative Names | soluble CD59, soluble Protectin, sProtectin |