Transferrin is a glycoprotein responsible for the transport of iron in the bloodstream, playing a critical role in iron homeostasis and cellular metabolism. In rats, as in humans, transferrin binds iron ions and delivers them to cells via transferrin receptors, helping regulate iron availability for processes such as hemoglobin synthesis and enzymatic reactions. Because iron levels must be tightly controlled to prevent deficiency or toxicity, transferrin serves as an important biomarker for assessing iron status, oxidative stress, and related metabolic conditions. Alterations in transferrin expression can indicate systemic iron imbalance, inflammation, or liver dysfunction.
A rat transferrin ELISA allows precise quantification of transferrin levels in serum, plasma, or tissue samples. In research settings, this assay is commonly used to study iron metabolism, anemia, and inflammatory responses in rat models of disease, including cancer, infection, and metabolic disorders. By tracking transferrin levels, researchers can evaluate the effects of genetic modifications, dietary interventions, or therapeutic agents on iron regulation and systemic health.
In a clinical context, rat transferrin ELISAs are primarily applied in preclinical studies to model human diseases. Measuring transferrin levels in these models helps assess the risk or progression of iron-related disorders, monitor responses to iron supplementation or chelation therapies, and investigate the role of iron metabolism in conditions such as chronic inflammation, liver disease, and cardiovascular dysfunction. This makes the assay a valuable tool for both mechanistic studies and translational research.
This product is manufactured in USA by Eagle Biosciences.
| Size | 1 x 96 Well |
| Sensitivity | 1.153 ng/mL |
| Dynamic Range | 6.25 ng/mL – 400 ng/mL |
| Incubation Time | 40 minutes |
| Sample Type | Serum, plasma |
| Storage | 2-8°C |
| Alternative Names | Serotransferrin, siderophilin, beta-1-globulin, and iron-binding glycoprotein. |