Hemopexin is a plasma glycoprotein that plays a critical role in heme scavenging and iron homeostasis. It binds free heme released during hemolysis or tissue injury, preventing heme-mediated oxidative damage and facilitating its clearance via the liver. In addition to its protective antioxidant function, hemopexin participates in inflammatory regulation and can influence immune responses. In rats, hemopexin levels are often studied as a biomarker of oxidative stress, hemolytic activity, and systemic inflammation, providing insights into pathophysiological processes in preclinical models.
A rat hemopexin ELISA allows for the quantitative measurement of hemopexin in serum, plasma, or other biological fluids. In research settings, this assay is commonly used to investigate hemolysis, liver injury, sepsis, and inflammatory disease models. By tracking hemopexin levels, researchers can assess the degree of oxidative stress and the effectiveness of therapeutic interventions aimed at reducing tissue damage or modulating immune responses.
While primarily a tool in preclinical research, hemopexin measurements have potential translational relevance for clinical studies. In humans, altered hemopexin concentrations are associated with hemolytic disorders, liver disease, and systemic inflammatory conditions. Insights gained from rat models can help inform clinical investigations, guide biomarker development, and support the evaluation of treatments targeting oxidative stress or inflammation in disease states.
This product is manufactured in USA by Eagle Biosciences.
| Size | 1 x 96 Well |
| Sensitivity | 1.358 ng/mL |
| Dynamic Range | 6.25 ng/mL – 400 ng/mL |
| Incubation Time | 1 hour 20 minutes |
| Sample Type | Serum, plasma |
| Storage | 2-8°C |
| Alternative Names | HPX, β-1–glycoprotein, and hemopexin glycoprotein. |