Rat Haptoglobin ELISA Kit
Haptoglobin is an acute-phase glycoprotein primarily produced by the liver that binds free hemoglobin released from erythrocytes, preventing oxidative damage and kidney injury while facilitating iron recycling. In rats, as in other mammals, haptoglobin levels rise in response to inflammation, infection, tissue injury, or stress, making it a sensitive biomarker of systemic inflammatory processes. Its regulation is closely linked to cytokine signaling, particularly interleukin-6, and it plays roles in immune modulation, antioxidant defense, and maintaining vascular homeostasis.
A rat haptoglobin ELISA provides a quantitative method for measuring circulating haptoglobin levels in serum, plasma, or other biological fluids. In research, it is widely used to assess inflammatory responses in preclinical models of infection, autoimmune disease, metabolic disorders, and organ injury. By monitoring haptoglobin fluctuations, researchers can evaluate disease progression, the efficacy of anti-inflammatory treatments, or the impact of experimental interventions on systemic stress and inflammation.
In a clinical context, measuring haptoglobin can assist in evaluating hemolytic conditions, such as anemia resulting from red blood cell destruction, as low haptoglobin levels indicate hemoglobin binding and clearance. While primarily used in veterinary or preclinical studies for rats, these assays help translate findings to human health by providing insights into acute-phase responses, immune system activation, and the potential for therapeutic targeting of inflammatory pathways.
This Rat Haptoglobin ELISA Kit is manufactured in USA by Eagle Biosciences.
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