Pig Immunoglobulin A (IgA) is a critical antibody isotype in the mucosal immune system, serving as the first line of defense at mucosal surfaces such as the gut, respiratory tract, and urogenital tract. It exists mainly as a dimer in secretions, where it neutralizes pathogens and prevents microbial adhesion without triggering inflammation. The Pig IgA ELISA (Enzyme-Linked Immunosorbent Assay) is a quantitative immunoassay designed to measure total or antigen-specific IgA levels in porcine serum, saliva, milk, or mucosal secretions. Using species-specific antibodies and enzyme-linked detection, it provides a sensitive and accurate measure of IgA concentration, reflecting mucosal and systemic immune status.
In research, the Pig IgA ELISA is a powerful tool for studying mucosal immunity in pigs, which are a valuable model for human gastrointestinal and respiratory diseases due to their physiological similarity. It is used to evaluate vaccine-induced immune responses, especially for oral or intranasal vaccines that target mucosal surfaces. Researchers also use the assay to assess gut barrier health, enteric infections, weaning stress, and immune development in neonatal and growing pigs. Measuring IgA provides insight into the effectiveness of immunomodulatory treatments, probiotics, and feed additives designed to enhance mucosal immune protection in both veterinary and translational studies.
Clinically, IgA is an important biomarker of mucosal immune competence and immune dysregulation, with low or aberrant levels associated with susceptibility to infections or autoimmune-like conditions. In translational settings, pig IgA data help predict mucosal vaccine efficacy and guide the development of oral and respiratory immunotherapies relevant to human medicine. In veterinary applications, the Pig IgA ELISA supports herd health monitoring and vaccine evaluation by tracking mucosal immunity in swine populations. In summary, the Pig IgA ELISA is a quantitative biomarker assay essential for understanding mucosal immune function, enabling both veterinary health assessment and translational research into mucosal immunology and vaccine design.
This product is manufactured in USA by Eagle Biosciences.