N1-Acetyl-Spermidine ELISA Kit

N1-Acetyl-Spermidine ELISA Kit

N1-Acetylspermidine is a metabolite of spermidine, a polyamine involved in cellular growth, differentiation, and apoptosis. Polyamines like spermidine are essential for stabilizing DNA, regulating gene expression, and modulating ion channels, and their acetylation plays a key role in controlling intracellular polyamine levels and excretion. Elevated levels of N1-Acetylspermidine have been associated with increased cellular proliferation and metabolic activity, making it a potential biomarker for cancer, neurodegenerative diseases, and other conditions involving altered polyamine metabolism.

The N1-Acetylspermidine ELISA (enzyme-linked immunosorbent assay) allows for sensitive and specific quantification of this metabolite in serum, plasma, urine, or tissue samples. In research settings, it is used to investigate polyamine metabolism, study the regulation of cell growth, and explore the role of acetylated polyamines in disease processes. Researchers also use the assay to monitor changes in N1-Acetylspermidine levels in response to experimental treatments or metabolic interventions.

In clinical applications, measuring N1-Acetylspermidine can help in the assessment of disease progression and therapeutic efficacy, particularly in oncology and metabolic disorders. Its levels may serve as a non-invasive biomarker for early detection, prognosis, or monitoring of treatment responses in conditions characterized by dysregulated polyamine metabolism, providing valuable insights into patient management and personalized therapy strategies.

This N1-Acetyl-Spermidine ELISA Kit is manufactured in France by ImmuSmol.