Mouse IgG1 ELISA Kit

Mouse IgG1 ELISA Kit

The Mouse IgG1 ELISA Kit is designed to quantitatively measure immunoglobulin G1 (IgG1) in mouse serum, plasma, or other biological samples. IgG1 is one of the major IgG subclasses in mice and is strongly associated with Th2-type immune responses, including antibody-mediated immunity, allergic sensitization, and responses to certain protein antigens. Because IgG1 levels can reflect immune polarization, antigen exposure, and humoral immune activation, this biomarker is frequently used to characterize the nature and strength of adaptive immune responses. ELISA-based detection offers high specificity and sensitivity, making it a reliable method for tracking IgG1 dynamics across experimental conditions.

In research settings, the Mouse IgG1 ELISA Kit is commonly employed in immunology, vaccine development, and allergy studies. It allows investigators to monitor IgG1 production following immunization, infection, or allergen exposure, helping to delineate Th1/Th2 balance by comparing IgG1 to IgG2a or other subclasses. The kit is also useful in evaluating antibody responses in transgenic mouse models, assessing immune responses to therapeutic proteins, and studying mechanisms of tolerance or hypersensitivity. Because IgG1 is a key indicator of a humoral, Th2-skewed response, its measurement provides important mechanistic insights into immune regulation.

Although the assay itself is not used in clinical diagnostics, data generated from mouse IgG1 studies contribute to translational research aimed at improving vaccines, biologic therapies, and immunomodulatory treatments. By modeling antibody subclass responses in mice, researchers can predict the immunogenicity, efficacy, or safety of candidate therapeutics before moving into human trials. Overall, the Mouse IgG1 ELISA Kit serves as a foundational tool for exploring adaptive immunity, optimizing vaccine formulations, and guiding preclinical immunology research.

This Mouse IgG1 ELISA Kit is manufactured in USA by Eagle Biosciences.