Mouse Anti-Human FKBP51 Monoclonal IgG1 Antibody
FKBP51 (FK506-binding protein 5) is a co-chaperone of the Hsp90 complex and a key regulator of glucocorticoid receptor sensitivity, stress response, and protein folding. In the brain, FKBP51 modulates neuronal plasticity, inflammation, and tau protein stability—factors central to neurodegenerative disease progression.
Elevated FKBP51 expression has been observed in Alzheimer’s disease and is associated with increased tau aggregation and impaired autophagy. Its role in stress hormone signaling also links FKBP51 to mood disorders and cognitive decline, making it a molecular bridge between chronic stress and neurodegeneration.
Targeting FKBP51 offers a novel approach to modulate stress-related neurotoxicity and restore proteostasis in aging and diseased brains.
This Mouse Anti-Human FKBP51 Monoclonal IgG1 Antibody is manufactured in Canada by StressMarq.
