Mouse Anti-Human Antibody (MAHA) refers to the immune response in mice against human proteins, particularly humanized monoclonal antibodies. This response is significant in preclinical research involving humanized therapeutics, as the presence of MAHA can interfere with the efficacy and interpretation of these treatments. MAHA detection is crucial for assessing potential immunogenicity and ensuring the reliability of preclinical data.
In both research and clinical settings, the presence of MAHA can lead to false positives or negatives in immunoassays, affecting the outcomes of studies involving humanized monoclonal antibodies. Therefore, monitoring MAHA levels is essential to avoid misleading conclusions and to optimize the design and interpretation of preclinical studies.
This product is manufactured in USA by Eagle Biosciences.
| Size | 1 x 96 Well |
| Sensitivity | Cut-off |
| Dynamic Range | 0 – 27 ug/mL |
| Incubation Time | 2 hours |
| Sample Type | Serum, Plasma |
| Immunogen | |
| Source Species | |
| Specificity | |
| Expression System | |
| Clone | |
| Group | |
| Alpha Chain | |
| Beta Chain | |
| Peptide | |
| Peptide Source | |
| Format | |
| Buffer | |
| Concentration | |
| Storage | 2-8°C |
| Alternative Names | MAHA, Mouse Anti-Human Ab |
| Instructions For Use | https://eaglebio.com/wp-content/uploads/2025/05/RUO-MAH11-K01_MAHA_ELISA_Assay_Kit_Package_Insert.pdf |
| MSDS | https://eaglebio.com/wp-content/uploads/2016/12/MAH11-K01-Mouse-Anti-Human-Antibody-ELISA-MSDS.pdf |