Kynurenic Acid ELISA Kit

Kynurenic Acid ELISA Kit

Kynurenic acid (KYNA) is a metabolite of the essential amino acid tryptophan and a key component of the kynurenine pathway, which regulates immune response, neuroprotection, and neurotoxicity. It functions as an endogenous antagonist of excitatory neurotransmitter receptors, including NMDA and α7 nicotinic acetylcholine receptors, and has been implicated in modulating inflammation and oxidative stress. Abnormal levels of kynurenic acid have been associated with neurological disorders, psychiatric conditions, and immune dysregulation, making it a valuable biomarker for studying metabolic and neuroinflammatory pathways.

The kynurenic acid ELISA (enzyme-linked immunosorbent assay) provides a sensitive and quantitative method for measuring KYNA levels in plasma, serum, cerebrospinal fluid, or other biological samples. In research settings, this assay is used to investigate the role of the kynurenine pathway in neurodegenerative diseases, psychiatric disorders, inflammation, and cancer. Researchers can monitor how alterations in KYNA concentrations correlate with disease progression, immune activity, or treatment responses, providing insights into pathophysiological mechanisms.

In clinical applications, kynurenic acid measurement can assist in evaluating metabolic or neurological conditions where the kynurenine pathway is dysregulated. It can serve as a biomarker for early detection or monitoring of diseases such as schizophrenia, depression, Alzheimer’s disease, and chronic inflammatory disorders. By providing a quantitative assessment of KYNA, ELISA-based assays help clinicians and researchers track biochemical changes, evaluate therapeutic interventions, and better understand patient-specific disease mechanisms.

This Kynurenic Acid ELISA Kit is manufactured in by ImmuSmol.