Human IgA ELISA Kit
**IgA ELISA Kit: Biomarker Background and Applications**
Immunoglobulin A (IgA) is a critical antibody isotype predominantly found in mucosal secretions such as saliva, tears, and intestinal fluids, as well as in serum. It plays a central role in mucosal immunity by neutralizing pathogens and preventing their adherence to epithelial surfaces. In addition to its immunoprotective functions, IgA levels can reflect various physiological and pathological conditions, including infections, autoimmune disorders, and certain chronic inflammatory diseases. IgA dysregulation has also been linked to conditions like IgA nephropathy, celiac disease, and respiratory infections, making it a valuable biomarker for both research and clinical diagnostics.
The IgA ELISA (Enzyme-Linked Immunosorbent Assay) kit is designed to quantitatively measure IgA levels in biological samples such as serum, plasma, saliva, or other body fluids. The assay utilizes specific antibodies to capture IgA and a detection system, often colorimetric, to quantify the concentration with high sensitivity and specificity. Its ease of use, reproducibility, and scalability make it an indispensable tool for immunological research, including studies of mucosal immunity, vaccine response, and infection monitoring.
In the clinical setting, IgA ELISA kits are widely used for diagnostic and monitoring purposes. For example, they help detect elevated IgA levels in autoimmune or inflammatory disorders, assess immunodeficiency states, and monitor therapeutic responses. Additionally, IgA ELISAs can be used to evaluate specific IgA antibodies against pathogens, such as in celiac disease (anti-gliadin or anti-tTG IgA) or respiratory infections, providing insights into both systemic and mucosal immune responses. Overall, IgA ELISA kits bridge research and clinical applications by offering a reliable, quantitative method for studying IgA-related immunity and disease processes.
If you want, I can also make a **more concise version** suitable for a research paper or product brochure. Do you want me to do that?
This Human IgA ELISA Kit is manufactured in USA by Eagle Biosciences.
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