Chicken IgY ELISA Kit

Chicken IgY is the functional equivalent of mammalian IgG and is the predominant antibody found in the serum and egg yolk of chickens. It plays a central role in the avian immune system, providing both systemic and passive immunity to offspring through transfer to the egg. Structurally distinct from mammalian IgG, IgY does not bind mammalian Fc receptors or activate mammalian complement, which can reduce background interference in immunoassays. Its stability, specificity, and ethical advantages—since it can be harvested non-invasively from eggs—make IgY an attractive tool for both research and therapeutic applications.

The IgY ELISA (enzyme-linked immunosorbent assay) is used to quantify chicken IgY levels in serum, egg yolk, or other biological samples. In research, it serves as a model for studying avian immune responses, antibody production kinetics, and vaccine efficacy. IgY ELISAs are also widely employed in the development of novel immunotherapeutics and diagnostic reagents, as IgY antibodies can be raised against a variety of antigens with high specificity. Researchers take advantage of IgY’s lack of cross-reactivity with mammalian proteins to reduce nonspecific binding in assays.

In clinical and veterinary contexts, IgY ELISAs are useful for monitoring the immune status of poultry flocks, detecting exposure to pathogens, and evaluating vaccine responses. Additionally, IgY antibodies are being explored for passive immunotherapy in both animals and humans, targeting infections, toxins, and inflammatory conditions. Quantifying IgY levels helps assess the potency and quality of these antibodies for therapeutic or prophylactic applications, supporting both translational research and practical clinical interventions.

This product is manufactured in USA by Eagle Biosciences.