Chicken Immunoglobulin M (IgM) is the first antibody isotype produced by birds in response to infection or immunization, playing a central role in the early stages of the humoral immune response. IgM exists predominantly as a pentamer in circulation, allowing it to efficiently bind antigens and activate the complement system, providing immediate defense against pathogens. In chickens, IgM is particularly important for studying immune responses in both natural infections and vaccination protocols, as it reflects recent or primary exposure to antigens. Its levels can indicate the strength and timing of an immune response, making it a key biomarker in avian immunology.
Chicken IgM ELISA (enzyme-linked immunosorbent assay) is used to quantify IgM antibodies in serum, plasma, or egg yolk samples. In research, this assay enables the study of immune kinetics following vaccination or infection, assessment of maternal antibody transfer to chicks, and evaluation of immune responses to novel antigens or experimental vaccines. It also serves as a tool for monitoring immune system development and function in experimental avian models.
In clinical and veterinary applications, chicken IgM ELISAs are used to detect early-stage infections in poultry flocks, monitor the efficacy of vaccination programs, and support disease surveillance. Measuring IgM levels helps veterinarians identify recent exposures to pathogens before clinical symptoms appear, allowing for timely interventions to prevent disease spread. Additionally, it can assist in understanding immune deficiencies or abnormal immune responses in birds, guiding management and treatment decisions in both research and commercial poultry operations.
This product is manufactured in USA by Eagle Biosciences.
| Size | 1 x 96 Well |
| Sensitivity | 0.979 ng/mL |
| Dynamic Range | 3.125 ng/mL – 200 ng/mL |
| Incubation Time | 1 hour 10 minutes |
| Sample Type | Serum, plasma |
| Storage | 2-8°C |
| Alternative Names | Immunoglobulin M, Macroglobulin, and Pentameric Immunoglobulin. |