Nt-proBNP ELISA Assay: Product Highlights

Eagle Biosciences’ Cardiovascular line is a full list of unique assays for the
comprehensive determination of important and emerging biomarkers of
cardiovascular disease. Our NT-proBNP ELISA Assay Kit is one of the top assays in this Cardiovascular line offering a sensitive and specific means to assess BNP status. In addition, this assay kit
also provides excellent stability in
serum for reliable results and
a wide dynamic range thus enabling the accurate detection of the early stages
of heart failure.

EagleBio’s NT-proBNP Assay is an incredible tool for researchers, providing a more valuable, simple, cost-effective, and
flexible alternative to existing methods.

Why Measure NT-proBNP?

The N-terminal prohormone of brain natriuretic peptide (NT-proBNP) is
a 76 amino acid N-terminal protein that is cleaved to release brain natriuretic
peptide. Both NTproBNP and BNP are secreted mainly by the left cardiac
ventricle as a result of pressure overload and wall stretch. Elevated NT-proBNP
levels indicate the presence of ongoing myocardial stress and potentially an
underlying, possibly unsuspected, cardiac disorder.

NT-proBNP is the N-terminal 76 amino-acid
cleavage product of proBNP that is released from cardiac ventricles in response
to increased wall stress and volume overload. NT-proBNP has a longer half-life
in the circulation (120 minutes) compared with the C-terminal BNP peptide (20
minutes). Therefore, the measurement of NT-proBNP offers excellent stability in
serum/plasma for reliable results.

Key Advantages of EagleBio’s NT-proBNP
ELISA Assay Kit?

Simple ELISA method
Uniquely designed antibodies for enhanced cross-reactivity with Nt-proBNP 1-76
Excellent stability: Long half-life of 120 minutes allows for ease of measurement and valuable,
reliable results.
Flexible: Assay
format and short incubation time offers ability to run in all types of labs and
on various platforms-manual or automated.
Wide Dynamic Range: Allow for enhanced, accurate detection of the early stages of heart
failure.