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April 17, 2014:  Eagle Biosciences, Inc. is pleased to announce the product launch of a new Homoarginine ELISA assay kit which will be the first commercially available ELISA kit for homoarginine for researchers. Homoarginine is a non-essential cationic amino acid which is formed from lysine and show characteristics similar to arginine.

Dan Keefe, President of Eagle Biosciences, is thrilled about the launch of this kit, “This is an exciting time for Eagle. Studies have identified homoarginine as a potentially useful predictor of cardiovascular events and mortality as well as a possible indicator of chronic kidney disease. The homoarginine assay is a perfect complement to the gold standard assays we offer for ADMA, SDMA, and Arginine.”

Eagle anticipates offering promotional pricing in the coming months for researchers measuring Homoarginine, ADMA, SDMA, or Arginine. These assay kits are currently for research use only. 

February 2, 2014: Eagle Biosciences is excited to announce the product launch of two new assays: Big Endothelin-1 ELISA Assay Kit and Endothelin 1-21 ELISA Assay Kit. These ELISAs were developed and are manufactured by Biomedica Gruppe in Austria. Biomedica is at the forefront of innovation in research assays, delivering unique and reliable cardiovascular and bone metabolism immunoassays for researchers around the world. The Endothelin 1-21 ELISA and Big Endothlin-1 ELISA are just a couple of the multiple premier assays in Biomedica’s cardiovascular product line that not only offer direct measurement of these analytes but also provide a flexibility to run manually or in an automated system.

The Endothelin 1-21 ELISA Assay kit is designed for the detection and quantification of biologically active Endothelin 1-21. Big Endothelin-1, on the other hand is designed for the detection and quantification of the biologically inactive peptide and 38 amino-acid precursor, Big Endothelin-1. Some researchers believe that Big Endothelin-1’s huge advantage is its prolonged half-life of 30 minutes compared to endothelin, which is approximately 1.5 minutes. Collectively, these assays provide a comprehensive means to accurately and easily measure the endothelin system and circulating concentrations of endothelin. In addition, these products further expand Eagle’s growing Cardiac and Oxidative Stress product lines.

“Endothelin 1-21 and Big Endothelin-1 biomarkers are becoming increasingly more valuable in various areas of research and may ultimately play a significant role in the development and maintenance of anti-endothelin therapy.” said Dan Keefe, President of EagleBio. He continued, “There are several key attributes of these kits such as excellent sensitivity, use with multiple sample types, and small sample volume requirements which make these assay kits excellent tools for the evolving research in this field.”

Eagle is offering promotional pricing for researchers measuring Endothelin 1-21 and Big-Endothelin-1 through the next few months. These products are currently for research use only. Check out the Eagle website www.EagleBio.com or call 866-411-8023 for full details.

December 12, 2013: Eagle Biosciences announces the product launch of a new Anti-Zinc Transporter 8 ELISA.   This assay was carefully designed to utilize the ability of ZnT8 Abs to act divalently and to form a bridge between immobilized ZnT8 and ZnT8.

Anti-Zinc Transporter 8 ELISA Assay kit is capable of detecting and quantifying autoantibodies specific to R 325, W 325, or to residue 325 non-specific variants. This assay specificity was designed based on comprehensive human population gene polymorphism research in the field that supports human sera’s reaction to the alleles encoded with these three protein variants. This product further expands Eagle’s Endocrine product line and more specifically, it complements the other circulating autoantibody kits in this line: IAA ELISA Assay Kit, Anti-GAD (Glutamic Acid Decarboxylase) ELISA Assay Kit, and the Anti IA2 ELISA Assay Kit.

“Anti-Zinc Transporter 8, otherwise known as ZnT8 is a novel maker and a new antigenic target for Type 1 Diabetes,” said Dan Keefe, President of Eagle Biosciences. He continued, “We are proud to deliver new, unique solutions like our Anti-Zinc Transporter 8 ELISA that will assist our customers and benefit emerging areas of research. I have no doubt that this kit will be useful in studies surrounding the early detection of Type 1 and Type 2 Diabetes.”

Eagle is offering promotional pricing for researchers measuring insulin (Anti-Zinc Transporter 8, IAA, Anti-GAD, and Anti-IA2) through the next few months. This protein is currently for research use only. Check out the Eagle website www.EagleBio.com or call 866-411-8023 for fulDecember 12, 2013:
Eagle Biosciences announces the product launch of a new Anti-Zinc Transporter 8 ELISA.   This assay was carefully designed to utilize the ability of ZnT8 Abs to act divalently and to form a bridge between immobilized ZnT8 and ZnT8.

Anti-Zinc Transporter 8 ELISA Assay kit is capable of detecting and quantifying autoantibodies specific to R 325, W 325, or to residue 325 non-specific variants. This assay specificity was designed based on comprehensive human population gene polymorphism research in the field that supports human sera’s reaction to the alleles encoded with these three protein variants. This product further expands Eagle’s Endocrine product line and more specifically, it complements the other circulating autoantibody kits in this line: IAA ELISA Assay Kit, Anti-GAD (Glutamic Acid Decarboxylase) ELISA Assay Kit, and the Anti IA2 ELISA Assay Kit.

“Anti-Zinc Transporter 8, otherwise known as ZnT8 is a novel maker and a new antigenic target for Type 1 Diabetes,” said Dan Keefe, President of Eagle Biosciences. He continued, “We are proud to deliver new, unique solutions like our Anti-Zinc Transporter 8 ELISA that will assist our customers and benefit emerging areas of research. I have no doubt that this kit will be useful in studies surrounding the early detection of Type 1 and Type 2 Diabetes.”

Eagle is offering promotional pricing for researchers measuring insulin (Anti-Zinc Transporter 8, IAA, Anti-GAD, and Anti-IA2) through the next few months. This protein is currently for research use only. Check out the Eagle website www.EagleBio.com or call 866-411-8023 for full details. l details.

October 1, 2013: Nashua, NH: Eagle Biosciences announces the product launch of 7 new AT1R (Anti-Angiotensin II Receptor I Antibody) ELISA Assay kits. These assays are designed for the simple determination of human Anti-Angiotensin II Receptor I Antibodies in various immunoglobulin subclasses (IgG1, IgG2, IgG3, IgG4, and IgM) for screening in serum and plasma samples. These assay kits expand and complement Eagle’s oxidative stress product line which includes a vast array of assays for prominent biomarkers in the field.

“These ELISA kits have excellent analytical sensitivity, as low as 2.5 U/ml.” said Dan Keefe, President of EagleBio, “We are thrilled about this product launch because antibodies to angiotensin II receptor 1 are associated with multifaceted areas of research such as scleroderma, neurological diseases, and severe vascular rejection. The detection and screening of these antibodies will assist researchers as well as to support, manage, and better understand transplantation medicine, one of the most challenging and complex areas of modern medicine.”

Keefe continued, ” I have confidence that these AT1R ELISA assays will become a remarkable method for researchers in the field. Eagle continually seeks to satisfy the unmet needs of researchers and we have high hopes that these unique assay kits that are designed for human, mouse, or rat samples will do just that.”

Eagle is offering promotional pricing for researchers measuring AT1R (Anti-Angiotensin II Receptor I Antibody) through the next few months. These assay kits are currently for research use only. Check out the Eagle website www.EagleBio.com or call 866-411-8023 for full details.

June 5, 2013: Nashua, NH: Eagle Biosciences is proud to announce the product launch of a brand new Calprotectin ELISA assay kit that offers the widest measurement range of any available assay (1-2000 µg/g stool). The Calprotectin ELISA assay kit is designed for quick and easy determination of human Calprotectin (neutrophil cytoplasmic protein s100A8/A9, MRP 8/14) in stool samples. This launch further expands Eagle’s gastrointestinal assay line which already includes Alpha 1 Antitrypsin ELISA, Anti-Gliadin IgG ELISA, Anti-Gliadin sIgA/IgA ELISA, Celiac EmA (Anti- Endomysium Antibody) IgG ELISA, Eosinophil Derived Neurotoxin (EDN) ELISA, Myeloperoxidase (MPO) Stool/Urine ELISA, Rotavirus Antigen ELISA, and Secretory IgA (sIgA) ELISA.

“This ELISA kit has excellent analytical sensitivity, as low as 1.8 µg/g, and results can be produced in about two hours with the ease of incubations at room temperature.” said Dan Keefe, President of Eagle, “We are very excited about this product launch because calprotectin continues to gain enormous amounts of attention with regards to its significant role in gastrointestinal research and more specifically intestinal inflammation, especially now that the patent on measuring calprotectin in stool has expired and has opened the door for additional players into the market.”

Keefe continued, “I have strong expectations that our Calprotectin ELISA assay kit will become an outstanding tool to researchers in the field. The product offers significant flexibility and efficiency as the kit can be used with most open automated assay systems. Looking forward, we will soon be complementing our ELISA product line with Calprotectin ELISA for serum/plasma in addition to other new kits in development that include NGAL ELISA for stool and MPO ELISA for stool.”

Eagle will be offering promotional pricing for these products over the next few months. These products are currently for research use only. Check out the Eagle website www.EagleBio.com or call 866-411-8023 for full details. 

March 23, 2013: Berlin, Germany: BioTez Berlin-Buch GmbH signs Eagle Biosciences, Inc. as their exclusive distributor of the research use immunoassays for the North American market. BioTeZ Berlin-Buch GmbH is a company focused on biotechnological research and products. Eagle Biosciences is a premier supplier of unique and quality research and clinically relevant immunoassays and laboratory products.

Uwe Ahnert, Managing Director of BioTez is excited about the partnership, “With many years of successful experience in the research and clinical diagnostics markets, we are proud to have Eagle introduce our new diagnostic test recoveryELISA® which is aimed at testing therapeutic antibodies and antibody analogues. It is a patented technology and can be used for drugs already on the market like omalizumab or adalimumab as well as for drugs which are still in the development pipeline. The latter opens the possibility to combine drug and companion diagnostics from the very beginning.”

“BioTez is a very well established diagnostic company with a reputation of developing high quality products.” states Dan Keefe, President of Eagle Biosciences. “BioTez has a unique product line and they have enjoyed great success with clinical laboratories in Europe and Asia already. The recoveryELISA® product line is exceptional, supporting antibodies as drugs applications and enabling personalized medicine. Their diagnostic innovation is well tailored to support antibody design and drug design for pharmacokinetic and pharmacodynamic studies. “

Keefe continued, “I have strong expectations that our Calprotectin ELISA assay kit will become an outstanding tool to researchers in the field. The product offers significant flexibility and efficiency as the kit can be used with most open automated assay systems. Looking forward, we will soon be complementing our ELISA product line with Calprotectin ELISA for serum/plasma in addition to other new kits in development that include NGAL ELISA for stool and MPO ELISA for stool.”

Eagle will be offering promotional pricing for these products over the next few months. These products are currently for research use only. Check out the Eagle website www.EagleBio.com or call 866-411-8023 for full details.

Nashua, NH: Eagle Biosciences announces the product launch of a new Recombinant Human Insulin Biotin-labeled (Biotinylated Insulin). The Recombinant Human Insulin was developed by ibt – Immunological and Biochemical Testsystems GmbH using their exceptional biotinylation technology. This technology is unlike others in the market because it permits biotinylation without loss of activity and is designed specifically for Insulin, IGFs and analogs. This protein is offered in a lyophilized form which not only increases overall activity but also enhances stability.

This Recombinant Human Insulin was developed for use in numerous applications such as ELISA, FACS, MACS, ligand blotting, cross-linking studies, receptor binding, isolation, antigen processing experiments, clearance studies, cell therapy, tissue engineering, ligand blotting, immunohistochemistry, flow cytometry, and many other methods/techniques. It is a great addition to Eagle’s biotinylated protein product line which includes Recombinant Human IGFBP-2, IGFBP2, and IGFBP-6.

“The proteins offered in Eagle’s biotinylated protein product portfolio were the first commercially available.” said Dan Keefe, President of EagleBio, “And we continue to strive to bring interesting, esoteric products to our customers.” Keefe continued, “This protein meets and exceeds that criteria because it is not only one-of- kind in the market but also provide investigators the opportunity to apply it across multiple methods and areas of research.”

Eagle is offering promotional pricing for researchers measuring insulin (Recombinant Human Insulin, Biotin-labeled) through the next few months. This protein is currently for research use only. Check out the Eagle website www.EagleBio.com or call 866-411-8023 for full details.

Binzwangen, Germany: ibt – immunological and biochemical testsystems GmbH signs Eagle Biosciences, Inc. as their exclusive distributor of the research use biotinylated IGF’s and analogs, biotinylated IGFBP’s, Western-ligand blotting and ELISA Kits for the North American market.

ibt – immunological and biochemical testsystems GmbH (ibt) focuses on the development of antibodies and immunoassay kits for Insulin-like Growth Factors (IGF’s), Insulin-like Growth Factor Binding Proteins (IGFBP’s) and related molecules. ibt’s new biotinylation technology ensures full biological activity of the molecules. Applications of biotinylated IGF´s and other peptides and proteins are in western-ligand blotting, ELISA assay kits, protease assays, IHC, immunoprecipitation, cross-linking, cell sorting, immunohistochemistry, receptor binding and internalization studies and experimental cell therapy and tissue regeneration. Eagle Biosciences is a premier supplier of unique and quality research and clinically relevant laboratory products.

“ibt is a very well established diagnostic company with a reputation of developing high quality products.” states Dan Keefe, president of Eagle Biosciences. “ibt has a unique product line and they have enjoyed great success with researchers in Europe. They provide fantastic tools for measuring insulin, IGF-1 and IGFBP’s. In addition, they developed an assay for SDF-1 Alpha (CXCL 12) as well as assays for total and bioactive IGFBP-3 and IGFBP-4 in serum, plasma, or biological fluids. We are very proud to promote the ibt product line in the US and Canada. “

Eagle is offering promotional pricing for researchers measuring IGFBP-3 and IGFBP-4 through the end of September 2012. These assay kits are currently for research use only. Check out the Eagle website www.EagleBio.com or call 866-411-8023 for full details.

Eagle Biosciences announces the product launch of 4 new catecholamine assays kits designed for serum, plasma, tissue, and other biological samples. The 4 ELISA kits include Noradrenaline Ultrasensitive ELISA Assay Kit which allows for sample size as low as 20 µl, Adrenaline Ultrasensitive ELISA Assay Kit with a sensitivity of 1.6 pg/ml , Dopamine Ultrasensitive ELISA Assay Kit with a sensitivity of 5.9 pg/ml , and Noradrenaline / Dopamine Combination Ultrasensitive ELISA Assay Kit which is intended for the quantitative determination of both Noradrenaline as well as Dopamine in all types of biological samples on 2 different 96-well microplates.

Developed and manufactured by DLD Diagnostika in Germany (www.DLD-Diagnostika.de), these new assays offer researchers new tools to measure catecholamines on various types of samples including serum, plasma, urine, tissue, cell culture, as well as many other types of biological samples. Each kit has an extraction plate and reagent set included to allow for great flexibility with sample types while still maintaining outstanding sensitivity.

“Eagle is quite energized to now offer these new catecholamine assay kits from DLD Diagnostika”, said Dan Keefe, President of Eagle Biosciences. “These are the most sensitive assays in the world for Adrenaline, Noradrenaline, and Dopamine. And with the included extraction plate and reagents, many different species samples like mouse, rat, and canine can be measured with these ELISA kits as well. This is great news for researchers.”

Eagle is offering promotional pricing for researchers measuring Noradrenaline, Dopamine, and Adrenaline through July 2012. These assay kits are currently for research use only. Check out the Eagle website www.EagleBio.com or call 866-411-8023 for full details.

Eagle Biosciences is excited to announce the introduction of a new assay for 25-OH Vitamin D by enzyme linked immunoassay (ELISA). Adding to their menu of more than 200 Assays, Eagle adds the 25-Hydroxy Vitamin D ELISA to other vitamin assays for Vitamin A/E, Vitamin C, Vitamin K1, as well as Vitamins B1, B2, and B6.

With millions of tests performed annually, 25-OH Vitamin D remains one of the fastest growing assays in the US. This new assay offered by Eagle is unique because it offers 100% cross reactivity with both major isomers of Vitamin D: Vitamin D2 and Vitamin D3 as well as offering outstanding sensitivity to 1.9 ng/mL.

“We are thrilled to be offering this 25-Hydroxy Vitamin D ELISA to the US market. We now can offer researchers a tool that can provide results in less than 3 hours using a simple ELISA format while still maintaining the most competitive pricing in the industry.” said Dan Keefe, President at Eagle. He continued,”Most 25-OH Vitamin D assays are either geared toward the high-throughput users or are strictly research assays that require extraordinary conditions like long incubation times or a 37°C incubation. Our new 25-OH Vitamin D ELISA blends the usability and convenience of clinical assays with the pricing and sensitivity of a research assay.”

Eagle anticipates offering promotional pricing in the coming months for researchers measuring 25-OH Vitamin D. These assay kits are currently for research use only. Check out the Eagle website www.EagleBio.com or call 866-411-8023 for full details.