ExoGAG Urine

ExoGAG Urine

The ExoGAG Urine precipitation reaction is based on the interaction between the precipitation solution and glycosaminoglycans located on the exosome surface. After a simple incubation, the exosomes can be isolated by a short centrifugation. This patented system allows the isolation of exosomes from a urine sample with a minimal amount of co-precipitated material, such as protein or genetic material (DNA, RNA, or microRNA).

Urine is a biofluid produced by the kidneys to eliminate waste products such us urea and metabolites from the body by the urinary tract. Urine also contains some epithelial and blood cells, bacteria, viruses and importantly also extracellular vesicles (among them exosomes).
Exosomes isolate from urine mirror molecular processes, both physiological and pathological conditions, that happen in kidney, urothelial and prostate tissue.
Remarkably, urine can be easily and frequently collected in large quantities in a non-invasive manner.
Exosome isolated from urine represent a good surrogate for the identification of informative biomarkers for renal-related diseases.

This ExoGAG Urine is manufactured in Spain by Nexotech.