ExoGAG Plasma

ExoGAG Plasma

The ExoGAG Plasma precipitation reaction is based on the interaction between the precipitation solution and glycosaminoglycans located on the exosome surface. After a simple incubation, the exosomes can be isolated by a short centrifugation. This patented system allows the isolation of exosomes from a plasma sample with a minimal amount of co-precipitated material, such as protein or genetic material (DNA, RNA, or microRNA).

Plasma is the liquid component of the blood obtained after removing its cellular fraction (erythrocytes, leukocytes and thrombocytes). Plasma is a source of proteins, cell-free nucleic acids, extracellular vesicles (among them exosomes) and metabolites. It can host exosomes from any cellular type of the body in both physiological and pathological conditions. Given this, plasma is one of the major sources of exosomes for clinical applications, since liquid biopsies represent a low-invasive procedure.
Exosome isolate from plasma represent a good surrogate for the identification of informative biomarkers for disease diagnosis, prognosis and longitudinal monitoring.

This ExoGAG Plasma is manufactured in Spain by Nexotech.