Mouse IgE ELISA Kit
The Mouse IgE ELISA Kit is designed to quantitatively measure immunoglobulin E (IgE) levels in mouse serum, plasma, or other biological samples. IgE is a class of antibody primarily involved in allergic responses and defense against parasitic infections. It binds to high-affinity FcεRI receptors on mast cells and basophils, triggering the release of histamine and other inflammatory mediators upon antigen exposure. Measuring IgE provides insight into allergic sensitization, immune dysregulation, and Th2-mediated immune responses. ELISA technology enables sensitive, specific, and reproducible quantification of IgE, making it a standard tool in immunological research.
In research settings, the Mouse IgE ELISA Kit is widely used in studies investigating allergy, asthma, atopic dermatitis, food allergies, and parasitic infections. It allows researchers to assess total IgE levels or, in some study designs, correlate IgE changes with allergen challenge, cytokine shifts, or therapeutic interventions such as monoclonal antibodies targeting IgE or its signaling pathways. Mouse models of allergy rely heavily on IgE quantification to evaluate disease severity, immune polarization, and the efficacy of novel immunomodulatory treatments.
While the mouse assay is not used directly for clinical diagnostics, IgE dynamics in mouse models provide translational value for understanding human allergic disease mechanisms and developing new therapies. Preclinical studies using this kit help validate IgE as a biomarker for hypersensitivity, guide dosing strategies for anti-IgE biologics, and support safety testing for allergen immunotherapy candidates. Thus, the Mouse IgE ELISA Kit serves as an essential tool for advancing allergy research and informing future clinical approaches to allergic and immune-mediated diseases.
This Mouse IgE ELISA Kit is manufactured in USA by Eagle Biosciences.
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