Anti-Tg (Thyroglobulin) ELISA Kit
High Sensitive Anti-Tg IgG is an autoantibody directed against thyroglobulin (Tg), a key precursor protein involved in the synthesis of thyroid hormones. The presence of anti-Tg autoantibodies in serum is commonly associated with autoimmune thyroid diseases, including Hashimoto’s thyroiditis and Graves’ disease. Detecting these autoantibodies is a routine clinical practice to aid in the diagnosis and monitoring of thyroid dysfunction. Anti-Tg antibodies are particularly valuable in assessing the autoimmune activity within the thyroid gland, where they correlate with underlying histological changes.
In the clinical setting, the detection of high sensitive anti-Tg IgG serves as a biomarker for patients presenting with thyroid disorders such as chronic thyroiditis, hypothyroidism, and thyrotoxicosis. Although anti-Tg antibodies are less frequently observed in thyroid tumors, their presence still contributes to the overall assessment of thyroid autoimmunity. The improved ELISA-based assays with enhanced sensitivity and reduced background reactivity in healthy populations—such as the EDI™ high sensitivity anti-Tg IgG test—offer a more reliable tool for identifying autoimmune thyroid conditions with greater specificity and diagnostic accuracy.
In research, high sensitive anti-Tg IgG is used to explore the pathogenesis of autoimmune thyroiditis and to monitor the effectiveness of treatment strategies aimed at modulating autoimmune responses. Its inclusion in diagnostic panels alongside anti-TPO antibodies helps provide a comprehensive view of thyroid autoimmunity, contributing to early detection, disease stratification, and management planning in both clinical trials and routine endocrinology practice.
This Anti-Tg (Thyroglobulin) ELISA Kit is manufactured in USA by Eagle Biosciences.
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