The Mouse C3 ELISA Kit is designed to quantitatively measure complement component 3 (C3) in mouse serum, plasma, or other biological samples. C3 is a central protein in the complement cascade—an essential part of innate immunity involved in pathogen clearance, inflammation, and immune regulation. Because C3 sits at the convergence point of all three complement pathways (classical, lectin, and alternative), its concentration and activation state serve as important indicators of immune system activity. ELISA-based detection enables sensitive and specific measurement of C3, allowing researchers to assess both baseline complement levels and changes in response to disease, injury, or experimental manipulation.
In research settings, the Mouse C3 ELISA Kit is widely used in studies focused on immunology, infectious disease, autoimmunity, and inflammatory disorders. It helps investigators quantify complement activation during conditions such as sepsis, arthritis, lupus-like disease models, kidney injury, and neuroinflammation. The assay is also useful in evaluating therapeutic interventions that target the complement pathway, including complement inhibitors, monoclonal antibodies, or gene-editing approaches. Because ELISA kits offer reproducible and high-throughput measurement, they are valuable for mechanistic studies, longitudinal monitoring, and biomarker discovery.
In preclinical and translational research, C3 measurement provides a functional biomarker for evaluating disease severity, inflammatory status, and treatment response. Although C3 testing is not typically used directly in clinical diagnostics for humans via mouse assays, insights from mouse C3 ELISA studies directly inform clinical strategies related to complement dysregulation, such as in autoimmune diseases, transplant rejection, and complement-mediated nephropathies. Thus, the Mouse C3 ELISA Kit serves as a crucial tool bridging basic complement biology with therapeutic development and translational immunology.
This product is manufactured in USA by Eagle Biosciences.
| Size | 1 x 96 Well |
| Sensitivity | 1.379 ng/mL |
| Dynamic Range | 3.125 – 200 ng/mL |
| Incubation Time | 50 minutes |
| Sample Type | Serum, plasma |
| Storage | 2-8°C |
| Alternative Names | Here are alternative names for a **Mouse C3 ELISA Kit**, each written in sentence format:
* This assay is also known as the **Mouse Complement C3 Quantification ELISA Kit**. |