Human [Arg3] IGF-I (Media Grade)

$2,485.00

Human [Arg3] insulin-like Growth Factor-I (IGF-I) is a 70 amino acid analogue of IGF-I featuring a substitution of Arginine for Glutamine at position 3. This modification results in increased potency in vitro and in vivo due to reduced binding to IGF binding proteins, while maintaining similar receptor affinity to native IGF-I. This product is intended for research use only and is not for diagnostic or therapeutic applications.

Human [Arg3] insulin-like Growth Factor-I (IGF-I) is a 70 amino acid analogue of IGF-I comprising the complete human IGF-I sequence with the substitution of an Arginine for the Glutamine at position 3. Human [Arg3] IGF-I is more potent than IGF-I in vitro and in vivo. This increased potency is due to reduced binding of human [Arg3] IGF-I to most of the IGF binding proteins which modify the biological actions of IGF-I. Human [Arg3] IGF-I binds to the type 1 IGF receptor with similar affinity to wild type IGF-I. This is a high quality research reagent for use in studies on cell growth, IGF receptors and IGF binding proteins.

Human [Arg3] IGF-I is offered to customers who prefer a full length IGF-I rather than the truncated Human Des [1-3] IGF-I which has similar properties.

Media grade Human [Arg3] IGF-I is a high quality reagent at an economical cost to enable studies where higher quantities of peptide are required.

This product is manufactured in Australia by GroPep Bioreagents.

Size	5 mg





Source Species	Recombinant

Expression System	Ecoli









Storage	2-8°C
Alternative Names	Human [Arg3] insulin-like Growth Factor-I (IGF-I)

Human [Arg3] IGF-I (Media Grade)

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