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image credit: Graphical Abstract, Authors
Jonathan J. Miner, Abdoulaye Sene,
Justin M. Richner, Gregory D. Ebel,
Michael S. Diamond, Rajendra S. Apte


Miner et al., Zika Virus Infection in Mice Causes Panuveitis with Shedding of Virus in Tears, Cell Reports (2016), https://dx.doi.org/10.1016/j.celrep.2016.08.079 

“Zika virus (ZIKV) is an emerging flavivirus that causes congenital abnormalities and Guillain-Barr√© syndrome. ZIKV infection also results in severe eye disease characterized by optic neuritis, chorioretinal atrophy, and blindness in newborns and conjunctivitis and uveitis in adults. We evaluated ZIKV infection of the eye by using recently developed mouse models of pathogenesis. ZIKV-inoculated mice developed conjunctivitis, panuveitis, and infection of the cornea, iris, optic nerve, and ganglion and bipolar cells in the retina.” Read More

Source: (https://www.cell.com/cell-reports/abstract/S2211-1247(16)31175-5)