EagleBio’s Creatinine Microplate Assay Kit Used in Studying  High Incidence of Lung Cancer in Singapore Women


A recent study was conducted at the Masonic Cancer Center, University of Minnesota utilizing EagleBio’s Creatinine Microplate Assay, a kit designed for the quantitative determination of creatinine in urine by a microplate assay. This assay is part of our Oxidative Assay Kit Line which is a comprehensive group consisting of a numerous valuable products for assisting scientists in fields of research such as diabetes, cancer, aging, and other similar areas of study. Check the product page for full details on the kit or view the links below to find a new publication referencing our Creatinine Microplate Assay.


Publication:

Elevated Levels of Mercapturic Acids of Acrolein and Crotonaldehyde in the Urine of Chinese Women in Singapore Who Regularly Cook at Home

Study Summary:

This study observed  a cohort of women who frequently used a wok for cooking but did not smoke cigarettes, drink alcoholic beverages, or participate in other health-risk behavior related to lung cancer. Researchers utilize EagleBio’s Creatinine Microplate Assay to measure and assess the creatinine levels as well as high throughput liquid chromatography-tandem mass spectrometry to measure 3-HPMA and HMPMA.

It was discovered that women had significantly increased levels of urinary 3-HPMA and HMPMA, the respective mercapturic acids of acrolein and crotonaldehyde, and the levels of the biomarkers increased with increasing cooking frequency. Such findings do in fact confirm results and observations from previous studies performed on a much smaller sampling of Chinese women.

In conclusion, with the results from this study as well as several other epidemiological studies reveal the need for improved ventilation and other preventative measures in order to effectively remove such cooking fumes.


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