Vitamin B6 refers to a group of related compounds—pyridoxine, pyridoxamine, and pyridoxal—that are converted in the body to the active coenzyme form, pyridoxal-5-phosphate (P5P). As a cofactor for more than one hundred enzyme reactions, vitamin B6 plays a vital role in amino acid metabolism, neurotransmitter synthesis, hemoglobin production, and lipid metabolism. Because of its broad biochemical importance, deficiency can lead to diverse symptoms including skin disorders, muscle weakness, mood changes, impaired protein synthesis, and insomnia. Low vitamin B6 levels are also associated with elevated homocysteine, making deficiency a risk factor for cardiovascular and vascular diseases.
Clinically, vitamin B6 measurement is useful for diagnosing deficiencies caused by malabsorption disorders (such as Crohn’s disease or celiac disease), chronic liver disease, dialysis, alcoholism, pregnancy, or long-term use of oral contraceptives and certain medications. Monitoring vitamin B6 status is also relevant in patients with homocystinuria, inflammatory conditions, or neurological symptoms that may stem from impaired neurotransmitter synthesis. Because of its key metabolic roles, vitamin B6 assessment is valuable in both clinical diagnostics and research exploring metabolic, neurological, and cardiovascular health.
The Vititamin B6 test kit uses a microbiological assay in which Saccharomyces cerevisiae demonstrates vitamin B6–dependent growth. After incubation, turbidity is measured by ELISA reader and compared to a standard curve, with bacterial growth directly proportional to vitamin B6 concentration. This method provides a sensitive and reliable tool for determining vitamin B6 levels in serum for both human and veterinary applications.
This product is manufactured in USA by Immundiagnostik AG.
