Thymosin beta-4 ELISA Kit

$2,265.00

The Thymosin beta-4 (ß4) ELISA Kit is an enzyme immunoassay intended for the quantitative determination of thymosin β4 in serum and thymus extract. For research use only. Not for use in diagnostic procedures.

Thymosin beta-4 (Tβ4) is a small, highly conserved peptide belonging to the beta-thymosin family, originally believed to be thymus-derived hormones but now recognized as ubiquitous across many tissues. With a molecular weight of approximately 5 kDa, Tβ4 is especially abundant in the spleen, thymus, lung, and peritoneal macrophages. It plays a central role in actin dynamics by binding monomeric actin in a 1:1 ratio, effectively acting as an actin buffer—sequestering G-actin to prevent premature polymerization and releasing it as needed for cytoskeletal remodeling.

In research and clinical contexts, thymosin beta-4 is notable for its involvement in processes such as cell differentiation, tissue regeneration, and immune modulation. It is secreted extracellularly and can be detected in plasma and wound fluid, where it contributes to wound healing and tissue repair. Its biological functions include promoting angiogenesis, enhancing cell migration (chemotaxis), inducing matrix metalloproteinases (MMPs), reducing inflammation, and modulating the proliferation of bone marrow stem cells.

Due to its wide-ranging effects, Tβ4 is being explored as a therapeutic biomarker and treatment agent in conditions involving tissue injury, inflammation, cardiovascular disease, and even cancer. Its regulation of actin and influence on cell motility and healing make it a candidate for regenerative medicine and immune-related therapies.

This product is manufactured in Germany by Immundiagnostik AG.

Size 1 x 96 Well
Sensitivity
Dynamic Range 0.16-10 µg/mL
Incubation Time 2.25 hours
Sample Type Serum, Thymus extract
Immunogen
Source Species
Specificity
Expression System
Clone
Group
Alpha Chain
Beta Chain
Peptide
Peptide Source
Format
Buffer
Concentration
Storage 2-8°C
Alternative Names Thymosin beta-4, Tβ4, thymosin β4, TB500, thymosin beta 4 sulfoxide, thymosin β-4 acetate, thymosin fraction 5 component B, Fx peptide.
Instructions For Use https://eaglebio.com/wp-content/uploads/2025/05/KR9520-Thymosin_beta4-ELISA-Kit-IFU.pdf
MSDS https://eaglebio.com/wp-content/uploads/2019/06/KR9520-thymosin-beta-4-elisa-assay-kit-MSDS.pdf

Product Citations