Thymosin alpha-1 (Tα1) is a naturally occurring peptide originally isolated from thymus fraction 5 and is known for its potent immunomodulatory properties. It primarily acts on T-helper cells and natural killer (NK) cells, enhancing the body’s immune response. In addition to its immunostimulatory role, thymosin alpha-1 has been shown to influence hormonal regulation in the hypothalamus, highlighting its broader systemic significance in immune-endocrine communication.
In clinical and research settings, thymosin alpha-1 has demonstrated therapeutic promise in several disease models, including liver and colon carcinomas, as well as leukemia. Its potential use as a prognostic biomarker in cancers such as colon carcinoma is currently under investigation, with early studies suggesting correlations between Tα1 levels and disease progression or response to treatment. These findings support its value in oncology for both monitoring and therapeutic support.
Furthermore, thymosin alpha-1 has been integrated into combined chemotherapy regimens, particularly in cases of bronchial carcinoma, where it may enhance the efficacy of conventional treatments. Its ability to restore or bolster immune function makes it a valuable tool in immunotherapy strategies, especially in immunocompromised individuals or in cancers where immune suppression is a hallmark of disease progression.
This product is manufactured in Germany by Immundiagnostik AG.