Sheep Immunoglobulin G (IgG) is a polyclonal antibody derived from the serum of sheep, commonly used in immunological research and clinical diagnostics due to its stability, specificity, and cross-species compatibility. Structurally, it shares the characteristic features of IgG molecules, including a Y-shaped configuration with two antigen-binding sites, making it suitable for various immunoassay formats. Sheep IgG is often employed as a secondary antibody or as a control in experimental setups due to its low background reactivity in many mammalian systems.
In research settings, sheep IgG serves as a valuable tool for immunoassay development, including ELISA, Western blotting, and immunohistochemistry. It is frequently conjugated with enzymes (e.g., HRP, AP) or fluorescent dyes for detection purposes. Clinically, sheep IgG is used in assay development for detecting human or animal biomarkers, particularly in bridging assays and anti-drug antibody (ADA) testing, where its immunogenic properties can help simulate or detect immune responses to therapeutic proteins. Its availability in well-characterized, purified formats makes it a reliable standard in both preclinical and regulated assay environments.
This product is manufactured in USA by Eagle Biosciences.