The **Rat L-FABP (Liver Fatty Acid–Binding Protein) ELISA Kit** measures levels of L-FABP, a small cytoplasmic protein highly expressed in hepatocytes and proximal renal tubular cells. L-FABP binds long-chain fatty acids and helps regulate lipid metabolism and oxidative stress responses. Because it is rapidly released into circulation or urine following hepatocellular injury or renal tubular damage, L-FABP has emerged as a sensitive biomarker for early organ injury—often rising before traditional markers such as ALT, AST, or creatinine.
In **research settings**, the Rat L-FABP ELISA Kit is widely used in studies of liver toxicity, nonalcoholic fatty liver disease (NAFLD), ischemia–reperfusion injury, drug-induced hepatotoxicity, and metabolic disorders. Its sensitivity makes it valuable for detecting subtle or early-stage hepatic stress in toxicology studies. Additionally, because L-FABP is also a marker of proximal tubular injury, it is employed in nephrology research to evaluate kidney damage in models of acute kidney injury, chronic kidney disease, and exposure to nephrotoxic compounds.
In **preclinical and translational applications**, measuring L-FABP helps assess the safety profiles of pharmaceuticals, chemicals, and biologics by providing early indication of liver or renal toxicity. Although L-FABP testing in rats is not used directly for clinical diagnoses in humans, its behavior parallels L-FABP biology across species, making it a valuable surrogate for predicting potential organ injury risks and informing dose selection, therapeutic monitoring strategies, and clinical trial design.
This product is manufactured in USA by Eagle Biosciences.
| Size | 1 x 96 Well |
| Sensitivity | 1.278 ng/mL |
| Dynamic Range | 3.125 ng/mL – 200 ng/mL |
| Incubation Time | 1 hour 20 minutes |
| Sample Type | Serum, plasma |
| Storage | 2-8°C |
| Alternative Names | 1. This assay is also known as a **Rat Liver Fatty Acid–Binding Protein ELISA Kit**. 2. Many researchers refer to it as a **Rat L-FABP Detection ELISA Kit**. 3. It may also be called a **Rat Liver FABP Quantification Kit**. 4. Some protocols describe it as a **Rat L-FABP Immunoassay Kit**. 5. It is sometimes listed as a **Rat Liver Fatty Acid Binding Protein Measurement Kit**. 6. Another common name is a **Rat L-FABP Analysis ELISA Kit**. 7. It can also be described as a **Rat L-FABP Quantitative ELISA Kit**. 8. In some catalogs, it is labeled as a **Rat Liver FABP Detection Assay Kit**. |