Rat IgM ELISA Kit

Rat IgM ELISA Kit

The **Rat IgM ELISA Kit** is designed to quantitatively measure immunoglobulin M (IgM) levels in rat serum, plasma, or other biological fluids. IgM is the first antibody isotype produced during an initial immune response, making it a key biomarker for early-stage infection, acute inflammation, and activation of the humoral immune system. Because IgM appears rapidly following antigen exposure and declines as IgG production rises, its presence and concentration can give insight into the timing and strength of an immune response. ELISA-based detection offers high specificity and sensitivity by using IgM-specific capture and detection antibodies, ensuring accurate measurement even in complex samples.

In **research settings**, the Rat IgM ELISA Kit is frequently used to study immune function, vaccine responses, autoimmune mechanisms, and infection models. It allows investigators to monitor early immunological changes, evaluate adjuvant or immunotherapy effects, and compare IgM responses across experimental conditions. The assay’s quantitative nature also supports kinetic studies, helping researchers track the progression from innate to adaptive immunity.

In **preclinical and translational contexts**, rat IgM measurement is useful for evaluating the safety and immunogenicity of drug candidates, biologics, and nanoparticles. Elevated IgM may indicate unintended immune activation or early hypersensitivity reactions, making it a valuable biomarker in toxicity and immunotoxicology studies. Although IgM testing in rats is not directly used for clinical decision-making in humans, data generated from these assays can inform clinical trial design, dose selection, and risk assessment by revealing immunological trends relevant to human physiology.

This Rat IgM ELISA Kit is manufactured in USA by Eagle Biosciences.