Rabbit Plasminogen ELISA Kit

Plasminogen is a crucial zymogen in the fibrinolytic system, acting as the inactive precursor of plasmin, an enzyme responsible for breaking down fibrin clots. In rabbits, as in humans, plasminogen plays a central role in maintaining blood fluidity, tissue remodeling, and wound healing. It is primarily synthesized in the liver and circulates in plasma, where it can be activated by tissue-type or urokinase-type plasminogen activators (tPA and uPA) to form plasmin. Beyond clot dissolution, plasminogen is involved in inflammatory responses and extracellular matrix degradation, making it an important biomarker for studying both normal physiological processes and disease states involving proteolytic activity.

The rabbit plasminogen ELISA provides a sensitive and specific method for measuring plasminogen levels in plasma, serum, or other biological samples. In research settings, this assay is commonly used to investigate the mechanisms of fibrinolysis, thrombosis, and wound healing, as well as to study the role of plasminogen in inflammation, tissue repair, and cancer progression. By quantifying plasminogen, researchers can assess how experimental treatments or genetic modifications affect the fibrinolytic pathway in rabbit models, which are often used as preclinical analogs for human disease.

In clinical and translational research contexts, rabbit plasminogen ELISAs are valuable for evaluating congenital or acquired plasminogen deficiencies, which can lead to impaired wound healing or abnormal clot formation. The assay also enables monitoring of therapeutic interventions targeting the fibrinolytic system and provides insights into hemostatic balance, liver function, and disease progression. Overall, measuring plasminogen in rabbits supports both basic research and the development of potential treatments for disorders involving fibrinolysis and tissue remodeling.

This product is manufactured in USA by Eagle Biosciences.