Rabbit Immunoglobulin A (IgA) is a critical component of the mucosal immune system, functioning as the primary antibody in secretions such as saliva, tears, and intestinal fluids. IgA plays a key role in neutralizing pathogens at mucosal surfaces, preventing their adhesion and invasion, and modulating immune responses to maintain homeostasis. In rabbits, IgA is structurally similar to that in other mammals, making it a valuable model for studying mucosal immunity, antibody responses, and vaccine efficacy. Its quantification is important for understanding immune function in both normal and disease states.
The rabbit IgA ELISA is a sensitive assay designed to measure IgA concentrations in serum, plasma, or mucosal secretions. In research settings, it is commonly used to evaluate immune responses following infection, vaccination, or experimental manipulation, helping to track the development of mucosal immunity or systemic IgA responses. It is also used in studies of autoimmune disorders, allergy models, and gastrointestinal or respiratory infections, where IgA dynamics are crucial for disease progression and immune protection.
Although rabbit IgA ELISAs are primarily a research tool, they can have translational applications in clinical and veterinary studies. For example, they can assist in monitoring immune status in rabbits used as models for human disease, evaluating antibody-mediated protection in vaccine trials, or studying mucosal immunity defects. By providing quantitative data on IgA levels, these assays help researchers and clinicians understand immune competence and the effectiveness of therapeutic or prophylactic interventions.
This product is manufactured in USA by Eagle Biosciences.
| Size | 1 x 96 Well |
| Sensitivity | 5.137 ng/mL |
| Dynamic Range | 6.25 ng/mL – 400 ng/mL |
| Incubation Time | 50 minutes |
| Sample Type | Serum, plasma |
| Storage | 2-8°C |
| Alternative Names | Immunoglobulin A, sIgA, secretory IgA, and serum IgA. |