Porcine haptoglobin (Hp) is an acute-phase glycoprotein primarily produced by the liver in response to inflammation, infection, or tissue injury. It functions mainly to bind free hemoglobin released during hemolysis, preventing oxidative damage and renal injury. In pigs, Hp is a sensitive biomarker of systemic inflammation, with serum concentrations increasing significantly during infection, stress, or trauma. The Porcine Haptoglobin ELISA (Enzyme-Linked Immunosorbent Assay) is a quantitative immunoassay designed to measure Hp levels in serum or plasma, providing an accurate reflection of the animal’s acute-phase response and overall inflammatory status.
In research, porcine haptoglobin is widely used to monitor acute-phase and inflammatory responses in experimental models of infection, vaccination, or stress. Its measurement helps evaluate the severity of disease, monitor immune system activation, and assess therapeutic interventions. Researchers often use Hp ELISA in studies of bacterial, viral, or parasitic infections, as well as in models of metabolic or cardiovascular stress, to track systemic inflammation over time. Its sensitivity to inflammatory stimuli makes it particularly useful in early detection of subclinical disease or immune challenges in pigs.
Clinically, Hp serves as a diagnostic and prognostic biomarker in swine veterinary practice, indicating inflammation, infection, or tissue damage. Elevated Hp levels can guide management of herd health, evaluate responses to vaccination, or detect early disease outbreaks. In translational research, the pig model’s similarity to human inflammatory responses makes haptoglobin a valuable biomarker for preclinical studies, including drug safety assessment, anti-inflammatory therapy evaluation, and modeling systemic inflammatory conditions. In summary, porcine haptoglobin ELISA is a quantitative biomarker assay essential for assessing inflammation and acute-phase responses, with applications in both research and veterinary clinical practice.
This product is manufactured in USA by Eagle Biosciences.