Fibrinogen is a large, soluble plasma glycoprotein (≈340 kDa) synthesized primarily in the liver and composed of three pairs of polypeptide chains (Aα, Bβ, and γ). It plays a central role in the coagulation cascade, being converted by thrombin into insoluble fibrin during blood clot formation. In pigs, fibrinogen shares high sequence and structural homology with its human counterpart, making it an important biomarker in translational and veterinary research. The Pig Fibrinogen ELISA (Enzyme-Linked Immunosorbent Assay) is a quantitative immunoassay designed to measure fibrinogen concentrations in porcine plasma or serum, using species-specific antibodies to produce a signal proportional to fibrinogen levels.
In research settings, the Pig Fibrinogen ELISA is widely used to assess hemostatic function, inflammatory status, and tissue injury in porcine models. Because fibrinogen acts as an acute-phase reactant, its levels rise in response to infection, inflammation, trauma, or surgical stress. Researchers use the assay in cardiovascular, sepsis, coagulation disorder, and wound-healing studies to monitor systemic inflammation and clotting dynamics. Pigs are physiologically similar to humans, so measuring fibrinogen in pig models helps evaluate anticoagulant drugs, biomaterial compatibility, and inflammatory responses with strong translational relevance.
Clinically, fibrinogen is a well-established biomarker of coagulation and inflammation, used to monitor disorders such as disseminated intravascular coagulation (DIC), liver disease, and cardiovascular risk. The pig model’s similarity to human coagulation physiology makes fibrinogen ELISA data valuable for preclinical drug testing and biomedical device development. In translational research, fibrinogen measurement supports evaluation of hemostatic therapies, anti-inflammatory agents, and surgical outcomes. In summary, the Pig Fibrinogen ELISA is a quantitative biomarker assay essential for studying coagulation, inflammation, and tissue repair in translational research, bridging preclinical findings in pigs with human clinical applications.
This product is manufactured in USA by Eagle Biosciences.