Noradrenaline (Norepinephrine) ELISA Kit

Noradrenaline (also called norepinephrine) is both a neurotransmitter and a hormone that plays a crucial role in the body’s stress response and regulation of physiological functions such as attention, arousal, and blood pressure. It is synthesized primarily in the locus coeruleus of the brainstem and released from sympathetic nerve endings in the peripheral nervous system. As a biomarker, noradrenaline reflects sympathetic nervous system activity and is tightly linked to the “fight or flight” response, influencing cardiovascular, metabolic, and neurocognitive processes. Its levels can be measured in plasma, urine, or cerebrospinal fluid, providing insights into autonomic regulation and neurochemical balance.

In research settings, noradrenaline serves as a valuable biomarker for studying stress physiology, mood and anxiety disorders, neurodegenerative diseases (such as Parkinson’s and Alzheimer’s), and cardiovascular regulation. Alterations in noradrenaline levels or signaling pathways can indicate dysregulation of the autonomic nervous system or central monoaminergic circuits. For example, elevated noradrenaline may mark chronic stress or hyperarousal, while reduced levels are often associated with depressive symptoms or neurodegeneration.

Clinically, noradrenaline measurements assist in diagnosing and managing conditions involving autonomic dysfunction (e.g., pheochromocytoma, orthostatic hypotension) and in guiding pharmacological interventions that target adrenergic receptors. Additionally, exogenous noradrenaline is used therapeutically as a vasopressor in acute care settings to manage hypotension and shock. Thus, noradrenaline serves both as a diagnostic and therapeutic biomarker bridging neurochemical, cardiovascular, and psychological research with clinical application.

This product is manufactured in Germany by DLD Diagnostika.