NGAL (Stool/Urine) ELISA Kit

$615.00

The Eagle Biosciences Human NGAL ELISA Kit is intended for use in the quantitative determination of human neutrophil gelatinase-associated lipocalin (Lipocalin-2 or NGAL) in feces. NGAL is extremely stable in feces. The Eagle Biosciences Human human neutrophil gelatinase-associated lipocalin (Lipocalin-2 or NGAL) ELISA Kit is for research use only and not to be used in diagnostic procedures.

SKU: NGL35-K01 Category: Tags: , ,

Neutrophil Gelatinase-Associated Lipocalin (NGAL), also known as Lipocalin-2, is a 25-kDa glycoprotein initially identified in neutrophil granules. It is now recognized as a sensitive biomarker involved in various physiological and pathological processes, particularly those related to inflammation, infection, and tissue injury. NGAL is rapidly upregulated in response to cellular stress and is released by neutrophils, renal tubular cells, and other epithelial cells following injury, making it a key early indicator in acute and chronic disease states. Its mRNA and protein expression are significantly elevated in injured tissues, especially in the kidneys, under ischemic or toxic conditions.

In clinical settings, NGAL is best known for its role as an early biomarker for acute kidney injury (AKI). It can be detected in blood and urine within hours of renal insult, preceding rises in traditional markers such as serum creatinine. This makes NGAL valuable for early diagnosis and risk stratification in critically ill or post-surgical patients. Beyond AKI, NGAL has been explored as a diagnostic and prognostic marker in chronic kidney disease (CKD), cardiovascular diseases, sepsis, and certain cancers, including breast and colorectal carcinomas. In research, NGAL serves as a molecular tool for understanding renal pathophysiology, the role of inflammation in disease progression, and drug-induced nephrotoxicity. Its multifaceted utility stems from its rapid kinetics and specificity for tissue injury, positioning NGAL as a crucial biomarker in both translational and clinical research contexts.

This product is manufactured in USA by Eagle Biosciences.

Size 1 x 96 Well
Sensitivity 10.4 pg/mL
Dynamic Range 1.08 – 97.2 µg/g
Incubation Time 2 hours
Sample Type stool, urine
Immunogen
Source Species
Specificity
Expression System
Clone
Group
Alpha Chain
Beta Chain
Peptide
Peptide Source
Format
Buffer
Concentration
Storage 2-8°C
Alternative Names Lipocalin-2 (LCN2), Siderocalin,24p3, Uterocalin
Instructions For Use https://eaglebio.com/wp-content/uploads/2014/06/RUO_NGL35-K01_NGAL_Stool_ELISA_Assay_Kit_Package_Insert.pdf
MSDS https://eaglebio.com/wp-content/uploads/2014/06/NGL35-K01-NGAL-Stool-ELISA-Kit-MSDS-1.pdf

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