Mouse IgG3 ELISA Kit

Mouse IgG3 ELISA Kit

The Mouse IgG3 ELISA Kit is designed to quantitatively measure immunoglobulin G3 (IgG3) levels in mouse serum, plasma, or other biological samples. IgG3 is one of the four IgG subclasses in mice and is characterized by its strong ability to activate complement and bind to Fc receptors, making it particularly relevant in early humoral immune responses. It is often produced in response to T-independent antigens such as polysaccharides and certain bacterial components. ELISA-based detection enables sensitive and specific quantification of IgG3, providing a reliable tool for monitoring subclass-specific antibody responses in immunological studies.

In research settings, the Mouse IgG3 ELISA Kit is valuable for evaluating immune responses to infections, vaccines, and adjuvants. Because IgG3 is associated with complement activation and robust opsonization, it is frequently measured in studies involving bacterial pathogens, sepsis models, and innate-like B-cell responses. Researchers also use IgG3 measurements to characterize antibody class switching, assess the quality of vaccine-induced humoral immunity, and investigate immune dysregulation in autoimmune or chronic inflammatory disease models. Tracking IgG3 levels can help distinguish between different types of immune responses and provide mechanistic insights into B-cell function.

Although the kit is not directly used in clinical diagnostics, data from mouse IgG3 studies contribute to translational research by informing vaccine design, understanding antibody subclass roles in disease, and guiding therapeutic antibody development. Mouse models allow scientists to explore how specific antibody subclasses—such as IgG3—correlate with protection or pathology, ultimately helping shape strategies for human immunotherapies and vaccines. Thus, the Mouse IgG3 ELISA Kit plays a key role in advancing basic and translational immunology through subclass-specific antibody profiling.

This Mouse IgG3 ELISA Kit is manufactured in USA by Eagle Biosciences.