Mouse Anti Angiotensin II Receptor 1 IgG Antibody ELISA Kit

The Mouse Anti–Angiotensin II Receptor 1 (AT1) IgG Antibody ELISA Kit is designed to detect and quantify IgG antibodies directed against the Angiotensin II Type 1 Receptor (AT1R) in mouse samples. AT1R is a G-protein–coupled receptor that plays a central role in the renin–angiotensin system, regulating blood pressure, vascular tone, and fluid balance. Autoantibodies targeting AT1R have been implicated in autoimmune conditions, cardiovascular diseases, and transplant rejection, making their measurement valuable for both mechanistic research and disease monitoring.

In this ELISA format, microplate wells are coated with recombinant or synthetic AT1R antigens to capture AT1R-specific IgG antibodies from mouse serum or plasma samples. After binding, an enzyme-linked secondary antibody produces a colorimetric signal proportional to the concentration of anti-AT1R IgG. This assay provides a sensitive, specific, and reproducible method for quantifying autoantibodies in preclinical or experimental studies.

Applications of the Mouse Anti–Angiotensin II Receptor 1 IgG Antibody ELISA Kit include investigating autoimmune-mediated cardiovascular dysfunction, monitoring antibody responses in mouse models of hypertension or transplant rejection, and evaluating the role of AT1R-targeting antibodies in pathological signaling. Measuring these antibodies provides insights into immune-mediated modulation of the renin–angiotensin system and supports research into potential therapeutic interventions.

This product is manufactured in Germany by CellTrend GmbH.